Cartilage (Bovine and Shark)
What does it do? Cartilage, derived from shark and bovine (cow) sources, is a type of connective tissue comprised of mucopolysaccharides, protein substances, calcium, sulfur, and collagen. Early research in the 1950s and 1960s, using chips of bovine cartilage inserted into wounds, demonstrated that cartilage enhances wound healing.1 2 Since then, cartilage has been investigated for its potential role in regulating immune function and to stop the growth of tumors.3 The role of shark cartilage in inhibiting angiogenesis (the growth of new blood vessels) is hypothesized to be beneficial in halting the growth and spread of cancer;4 however, this remains to be proven by research.
Where is it found? Cartilage is derived from either sharks or cows.
In what conditions might cartilage be supportive?
Who is likely to be deficient? Since it is not an essential nutrient, cartilage is not associated with deficiency states. A few studies suggest that individuals with cancer may benefit from cartilage supplements;5 6 however, well-designed research is lacking, and many experts question the use of cartilage in this regard. A similar situation is seen with the use of cartilage in individuals with arthritis.
How much should I take? Anyone who is interested in taking bovine or shark cartilage supplements should consult a nutritionally oriented doctor for advice.
Are there any side effects or interactions? Researchers have suggested that there might be some people who should not use cartilage supplement, including those with cardiovascular disease, women who want to be or are pregnant, nursing mothers, anyone having or having had surgery within thirty days, and athletes training intensely. None of these contraindications has been proven, however.
References:
1. Prudden JF, Allen J. The clinical acceleration of healing with a
cartilage application. JAMA 1965;192:352-6.
2. Prudden JF, Wolarsky E. The reversal by cartilage of the steroid-induced inhibition of
wound healing. Surg Gyn Obset 1967;125(7):109-13.
3. Prudden JF. The treatment of human cancer with agents prepared from bovine cartilage. J
Biol Res Mod 1985;4:551-84.
4. Lee A, Langer R. Shark cartilage contains inhibitors of tumor angiogenesis. Science 1983;221:1185-7.
5. Lane AW, Contreras E Jr. High rate of bioactivity (reduction in gross tumor size)
observed in advanced cancer patients treated with shark cartilage material. J
Naturopathic Med 1992;3:86-8.
4. Prudden JF. The treatment of human cancer with agents prepared from bovine cartilage. J
Biol Resp Modif 1985;4:551-84.
Copyright © 1998 Virtual Health, LLC
It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally-oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.The information presented in HealthNotes Online is for informational purposes only.