Senna (Cassia senna, Cassia angustifolia)

Photo copyright Steven Foster  

Parts used and where grown: The senna shrub grows in India, Pakistan, and China. The leaves and pods are used medicinally.

In what conditions might senna be supportive?

constipation

Historical or traditional use: People in northern Africa and southwestern Asia have used senna as a laxative for centuries. Because of its cathartic effect, it was considered a “cleansing” herb. Additionally, the leaves were sometimes made into a paste and applied to various skin diseases. Ringworm and acne were both treated in this way.

Active constituents: Senna contains anthraquinone glycosides known as sennosides. These molecules are converted by the normal bacteria in the colon into rhein-anthrone, which in turn has two effects. It first stimulates colon activity and thus speeds bowel movements. Second, it increases fluid secretion by the colon.1 Together, these actions work to get a sluggish colon functional again.

How much should I use? Many people use an herbal extract in capsules or tablets providing 10-60 mg of sennosides per day. This can be continued for up to ten days maximum. Use beyond ten days is strongly discouraged. If constipation is not alleviated within ten days, individuals should seek the help of a health care professional. Combination with herbal mint teas can help decrease cramping. Half the adult dose of senna can be safely used in children over the age of six as well.

Are there any side effects or interactions? Senna can cause the colon to become dependent on it to move properly. Therefore, senna must not be used for more than ten consecutive days. Chronic senna use can also cause loss of fluids, low potassium levels, and diarrhea, all of which can lead to dehydration and negative effects on the heart and muscles. Senna is safe for use in pregnancy and lactation but only under the supervision of a physician.2 3 It is also safe for children over the age of six.

References:

1. Leng-Peschlow E. Dual effect of orally administered sennosides on large intestinal transit and fluid absorption in the rat. J Pharm Pharmacol 1986;38:606-10.
2. Mengs U. Reproductive toxicological investigations with sennosides. Arzneim Forsch Drug Res 1986;36:1355-8.
3. Faber P, Strenge-Hesse A. Relevance of rhein excretion into breast milk. Pharmacol 1988;36(suppl 1):212-20.

 

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The information presented in HealthNotes Online is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally-oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.